Description

BAM15A | CAS 210302-02-6 | ≥99.0% Purity | Laboratory Reagent | 5 grams

BAM15A (CAS 210302-02-6) is a specialized small-molecule compound – a synthetic mitochondrial protonophore uncoupler designed for advanced laboratory research and assay development. As a potent, cell-permeable reagent, BAM15A decouples oxidative phosphorylation (OXPHOS) from ATP synthesis in isolated mitochondria and cell cultures.

Unlike traditional uncouplers, research indicates BAM15A achieves mitochondrial depolarization without directly depolarizing the plasma membrane, making it a highly specific tool for investigating cellular energetics, oxygen consumption rates (OCR), and AMPK pathway activation in controlled in-vitro environments.

Chemically designated as N5,N6-Bis(2-Chlorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine, this compound belongs to the oxadiazolopyrazine family and serves as a valuable tool compound for studying mitochondrial function, bioenergetics, and cellular respiration.

Regulatory Notice: This material is sold strictly as an analytical reference standard and raw chemical reagent. It is not a finished drug product. Not intended for human consumption, in vivo research, diagnostic use, or therapeutic application.

Storage & Stability: Keep tightly sealed under inert gas at -20°C for long-term stability. Avoid repeated freeze-thaw cycles when dissolved in solution.